Pharmaceutical Processing

Application

Globaltherm^® L is a multi-purpose high performance benzyltoluene heat transfer fluid. It is for use in closed loop heat transfer systems. It is used predominantly in pharmaceutical industries and plastic processing and can be used in liquid and vapour form.

About Globaltherm® L

Globaltherm^® L benzyltoluene HTF is recommended for use in the temperature range from -30°C (-22°F) to 360°C (680°F), but can be used intermittently at film temperatures as high as 380°C (716° F). It can also be used in pressurised systems up to 360°C (680°F).

• Multi-purpose HTF in bulk outlet temperature ranges:
• -20°C (-4°F) to 280°C (536°F) in non-pressurised heat transfer systems
• 280°C (536°F) to 680°C (680°F) in pressurised or liquid-vapour heat transfer systems
• Globaltherm® L heat transfer fluid is non-corrosive
• Globaltherm® L can be used in the liquid or liquid/vapour phase due to its narrow boiling range of around 4°C (39°F)
• This heat transfer fluid has low pour point and pumping limit
• -30°C (-22°F)
• A thermal fluid with low viscosity for excellent heat transfer efficiency
• Globaltherm® L is a benzyl aromatic with excellent thermal stability

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Parameter	Unit	Code (ASTM / ISO)	Result
Appearance at 20°C	N/A	Visual	Liquid, clear
Composition	N/A	N/A	Benzyltoluene
Recommended bulk temperature	°C (°F)	N/A	330°C (650°F)
Extended maximum use temperature	°C (°F)	N/A	360°C (680°F)
Pumpability limit @ 2000	°C (°F)	N/A	380°C (715°F)
Normal boiling point	°C (°F)	N/A	278°C (532°F)
Pumpability limit @300	mm²/s (cSt)	N/A	-67°C (-88°F)
Pumpability limit @2000	mm²/s (cSt)	N/A	<-70°C (<-94°F)
Flashpoint COC	°C (°F)	ASTM D92	132°C (270°F)
Autoignition temperature	°C (°F)	ASTM E659	473°C
Autoignition temperature	°C (°F)	DIN 51794	510°C (950°F)
Pour point	°C (°F)	ASTM D97	-79°C (-110°F)
Kinematic viscosity @ 40°C	mm²/s	ASTM D445	2.78
Kinematic viscosity @ 100°C	mm²/s	ASTM D445	1.08
Average molecular weight	N/A	N/A	182.3
Density @ 25°C	Kg/m³	ASTM D4052	992
Coefficient of thermal expansion @ 200°C	N/A	N/A	0.000981°C
Moisture content maximum	ppm	ASTM E-203	300

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Application

GLOBALTHERM^® D Heat transfer fluid is a synthetic organic heat transfer fluid designed for relatively low-temperature use in the liquid phase in closed unpressurised heat transfer systems with forced circulation. The recommended upper temperature limit is 200°C.

This thermal fluid meets the FOA Regulation CFR 21 Part 178.3530 and 178.3650 and is primarily used in chemical processing applications.

About Globaltherm® D

Globaltherm^® D is recommended for use in heat transfer fluid systems operating in the temperature range from -80°C (-112°F) to 200°C (392° F).

• The product is most suitable for indirect cooling in refrigeration plants and in processes
• GLOBALTHERM® D Heat transfer fluid is thermally stable over the recommended usage range and provides good performance
•  GLOBALTHERM® D Heat transfer fluid is intended for use as heat-transfer medium in a closed plant.
• This heat transfer fluid does not corrode metallic materials used in the construction of heat transfer systems.
• This heat transfer fluid is a non-corrosive clear heat transfer fluid

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We provide advice on how to choose the most appropriate oil for your heat transfer applications and provide our customers with continued technical support.

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Application

Globaltherm^® J Heat transfer fluid is a superior high performance, energy efficient heat transfer fluid suitable for use in all kinds of industrial processes.

About Globaltherm® J

• This high performance heat transfer fluid is a mixture of isomers of an alkylated aromatic specially engineered for demanding low-temperature applications in liquid phase pressurised systems.
• Globaltherm® J Heat transfer fluid is a heat transfer agent suitable for applications requiring single fluid heating and cooling.
• This fluid is recommended for use in a temperature range from <-80°C (-112°F) up to a maximum bulk temperature of 315°C (600°F) in the liquid phase.
• This heat transfer fluid can also be used in vapour phase systems operating from 181°C to 315°C (358°F - 600°F).
• This heat transfer fluid offers outstanding low-temperature pumpability and excellent thermal stability for protection against accidental overheating.

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Parameter	Unit	Code (ASTM / ISO)	Result
Appearance	N/A	N/A	Clear, colourless liquid
Operating Range	°C (°F)	N/A	<-80°C to 315°C (<-110°F to 600°F)
Density @ 25°C	`kg/m³	ASTM D4052	860
Kin. Viscosity 40°C	mm²/s (cSt)	NTR	0.70
Kin. Viscosity 100°C	mm²/s (cSt)	NTR	0.40
Flash Point (closed)	°C	ASTM D93	57
Fire Point	°C	ASTM D92	60
Autoignition Point	°C	ASTM E659-78	420
Boiling Point	°C	NTR	181
Average Molecular Weight	NTR	NTR	134

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Application

Globaltherm^® S is a high performance heat transfer fluid for use in closed loop, non-pressurised heat transfer systems. Primary uses are chemical industries and plastic processing applications.

About Globaltherm® S

Globaltherm^® S is recommended for use in an upper temperature range from 250°C (482°F) to 350°C (662°F), but can be used intermittently at film temperatures as high as 380°C (716° F).

• Globaltherm® S heat transfer fluid is non-corrosive and can be used in non-pressurised heat transfer systems
• This heat transfer fluid can be used in systems requiring start-up temperatures as low as -5°C (23°F) without the need for heat tracing
• Globaltherm® S thermal fluid is thermally stable up to 300°C (572°F) and can be used for several years below this temperature with no adverse impact on performance
• Low viscosity 17cSt @ 40°C (104°F) with a pumping limit at -5°C (23°F)
• This thermal fluid has a high ASTM D93 flash point at 200°C – the highest in class
• Globaltherm® S has high thermal stress resistance in the bulk temperature range  from 60°C-350°C (140°F - 662°F)
• Globaltherm® S has a highly aromatic structure with a boiling point range of 385°C -395°C (725°F -743°F) - the highest in class

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Parameter	Unit	Code (ASTM / ISO)	Result
Appearance	N/A	N/A	Liquid, clear
Chlorine	ppm	DIN 51408	<10
Acid number	mg KOH/g	DIN EN ISO 2114	≤0.02
Density @ 20°C		DIN 51757	1.04 - 1.05
Viscosity @ 20°C	cSt	DIN 51562	42 - 52

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General product description	Unit	Code (ASTM/ISO/DIN)	Result
Boiling point at 1013 mbar	°C	ASTM D 1078	385 - 395
Pour point	°C	DIN ISO 6016	<-34
Flash point	°C	EN 22719	approx. 200
Autoignition temperature	°C	DIN 51794	approx. 500
Permissible heater outlet temperature	°C	NTR	350
Permissible heater film temperature	°C	NTR	380
Pumpability limit	°C	NTR	approx. -5

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Application

A highly efficient, non-toxic, food grade heat transfer fluid that is safe for incidental food contact in food processing plants and pharmaceutical facilities. Globaltherm FG is also Kosher and Halal certified.

About Globaltherm® FG

Made from severely hydro-treated base stocks, Globaltherm^® FG thermal fluid has outstanding thermal oxidation stability allowing operation at high temperatures for extended periods. It is non-hazardous, non-toxic, water white and odourless.

Highly efficient non-fouling NSF HT-1, FDA and USDA-Certified food grade heat transfer fluid is specified in a broad variety of industrial process applications in addition to food processing.

Globaltherm FG is also Kosher certified and Halal certified.

Globaltherm^® FG thermal fluid is a high efficiency heat transfer fluid specifically developed for non-pressurised, indirectly heated, liquid phase heat transfer systems found in food processing plants, pharmaceutical operations and other “food grade” applications that require bulk temperatures up to 326°C (619°F). FG is a mixture of exceptionally pure HT hydrocracked base oils.

 

• Globaltherm® FG thermal fluid is non-hazardous, non-toxic and odourless which means it requires no special handling and is not considered a “controlled substance” under United States OSHA, Canadian WHMIS or other work place regulations.
• Globaltherm® FG is NSF HT-1 Accredited
• The fluid is USDA CFR Title 21 178.3570 Compliant
• The fluid is also USFDA21 CR Compliant

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Parameter	Unit	Code (ASTM / ISO)	Result
Operating Range	°C (°F)	N/A	-20 to 326 (-4 to 619)
Appearance	N/A	N/A	Colourless transparent liquid with no odour.
Density @ 25°C	kg/m³	ASTM D4052	881
Kin. Viscosity 40°C	mm²/s (cSt)	ASTM D445	29.8
Kin. Viscosity 100°C	mm²/s (cSt)	ASTM D445	5.2
Flash Point PMC	°C	ASTM D93	210
Flash Point COC	°C	ASTM D92	216
Coefficient of Thermal Expansion	°C	NTR	0.00089/°C
Autoignition Point	°C	ASTM E659	350
Pour Point	°C	ISO 3016	-29
Neutralisation Nr (acid), TAN	mgKOH/g	ASTM D974	NTR
Maximum Bulk Temperature	°C	NTR	326
Maximum Film Temperature	°C	NTR	343
Boiling Point at 1013 mbar	°C	NTR	371
Average Molecular weight	NTR	NTR	350
Moisture Content	PPM	ASTM D6304	<100

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Globaltherm® Syntec: Synthetic heat transfer fluid (-3°C – 345°C)

Globaltherm® Syntec is the most popular synthetic heat transfer fluid for high-temperature operations. Engineered for exceptional performance, it operates efficiently at temperatures up to 345°C (653°F) and can be pumped down to -3°C (27°F).

This versatile thermal fluid is ideal for industries such as chemical processing, plastics manufacturing and biodiesel production, ensuring reliable performance in a wide range of indirect heating systems.

About Globaltherm® Syntec

Globaltherm® Syntec is built using advanced hydrogenated terphenyls chemistry, delivering superior results as a heat transfer fluid.

Designed for optimal thermal stability, this synthetic solution ensures operational efficiency even under demanding conditions. Its high-performance capabilities have made it a trusted choice for industrial fluid systems worldwide.

Whether it's maintaining service life in extreme conditions or maximising system efficiency, Globaltherm® Syntec outperforms traditional alternatives. This product is specifically formulated to help your heat transfer process run at full capacity while minimising maintenance and downtime.

Why choose Globaltherm® Syntec?

• Thermal stability: Engineered for excellent temperature tolerance and minimal degradation
• Operational efficiency: Helps maintain consistent perfor-mance across indirect heating systems
• Versatility: Suitable for a broad range of industries and applications
• Extended service life: Designed to reduce replacement frequency, saving costs over time
• Global reliability: Trusted in systems worldwide for con-sistent, high-level performance

With a proven track record in industrial thermal fluid systems, Globaltherm® Syntec offers unmatched reliability and efficiency. From enhancing the longevity of your heating system to supporting critical operations in high-temperature environments, this synthetic heat transfer fluid is designed to meet the unique demands of modern industries.

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Parameter	Unit	Code (ASTM/ISO)	Result
Appearance	N/A	N/A	Clear to pale yellow liquid with a characteristic odour
Operating Range	°C (°F)	N/A	-3° to 345 (27 to 653)
Density @25°C	kg/m³	ASTM D4052	1005
Kin. Viscosity @40°C	mm²/s (cSt)	ASTM D445	29.6
Kin. Viscosity @100°C	mm²/s (cSt)	ASTM D445	3.80
Flashpoint PMC	°C (°F)	ASTM D93	170 (338)
Flashpoint COC	°C (°F)	ASTM D92	184 (363)
Coeefficient of thermal expansion	°C	NTR	0.000819/°C
Autoignition point	°C (°F)	ASTM E659	374 (705)
Pour point	°C (°F)	ISO3016	-32 (-25.6)
Neutralisation Nr (acid), TAN	Mg KOH/g	ASTM D664	<0.2
Maximum Bulk Temperature	°C (°F)	NTR	345 (653)
Maximum film temperature	°C (°F)	NTR	375 (707)
Boiling point at mbar	°C (°F)	NTR	359 (678)
Average molecular weight	NTR	NTR	252 (485.6)
Moisture content	PPM	ASTM E-203	150 ppm

Technical notes

Note: The data provided represents typical performance characteristics and does not constitute a binding specification. These values are subject to allowable production tolerances and may vary across batches. For detailed technical guidance, contact our expert team. Abbreviations: OC, open cup test; COC, Cleveland open cup test; and, NTR, no test reported.

Contact us for more information on high temperature synthetic heat transfer oils.

 

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Streamline maintenance with Thermocare®

To complement the performance of the Globaltherm® range, the Thermocare® thermal fluid lifecycle maintenance program ensures your system operates efficiently and safely. With tailored packages like essential, optimum and ultimate, Thermocare® offers services ranging from live remote condition monitoring to comprehensive fluid maintenance for a fixed price.

This proactive approach reduces operational costs, enhances system safety and improves productivity through expert heat transfer fluid management.

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Need advice on selecting the correct synthetic fluid for your heat transfer applications? For expert guidance on thermal fluid solutions and technical support, call us at +44 (0)1785 760555 or get a quote below.

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Application

Globaltherm^® C is an organic stress resistant heat transfer fluid for use in the liquid or vapour phase in closed heat transfer systems with forced circulation.

About Globaltherm® C

Globaltherm^® C can be used in heat transfer systems for use as a liquid in non-pressurised systems from -90°C (-130°F) to 153°C (307°F) and in pressurised systems up to 300°C (572°F).

• This thermal fluid is for use in multi-purpose heat transfer systems where heating and cooling loops must be operated simultaneously
• Globaltherm® C is thermally stable up to 300°C (572°F) and particularly suitable in applications where exposure to air cannot be completely prevented
• This product provides turbulent flow and efficient heat transfer to -90°C (-112°F)
• Globaltherm® C can be used in systems requiring low start-up temperatures from -90°C (-130°F) without the need for heat tracing
• Globaltherm® C operates effectively in non-pressurised systems in the range -90°C - 180°C (-112°F - 356°F)
• This heat transfer fluid is non-corrosive.

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Parameter	Unit	Code (ASTM / ISO / DIN)	Result
Appearance at 20°C	N/A	Visual	Liquid, clear
Ethylbenzene Content	% by volume	GC	≤0.5
Water	% by mass	Din 51777	≤0.03
Density @ 20°C	g/ml	DIN 51757	0.855 - 0.865
Viscosity 20°C	mm²/s	DIN 51562	0.5 - 1.0
Boiling Range at 1013 mbar	°C	ASTM D1078	about 153
Pour Point	°C	DIN ISO 3016	< -90
Flash Point	°C	EN 22719	about 31
Ignition Temperature	°C	DIN 51794 (ASTM D659)	about 420
Permissible Heater Outlet Temperature	°C	NTR	300
Permissible Heater Film Temperature	°C	NTR	320
Pumpability Limit	°C	NTR	NTR

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Application

Globaltherm® GT06 is a premium synthetic heat transfer fluid engineered for use in systems requiring both heating and cooling.

Globaltherm® GT06 is widely used in the pharmaceutical, speciality, and fine chemical industries, where precise thermal control is critical.

Globaltherm® GT06 offers outstanding thermal stability and performance across a broad temperature range, operating from -40°C to +290°C in bulk and up to +350°C under pressure in closed systems. Its excellent low-temperature fluidity and high-temperature resilience support rapid cycling, energy efficiency, and system reliability.

Globaltherm^® GT06 and its direct alternative Jarytherm^® BT06 are both high performance synthetic heat transfer fluids. 

About Globaltherm® GT06

A key benefit of Globaltherm® GT06 is its low viscosity at low temperatures, which ensures excellent fluid mobility and pumpability even in sub-zero environments. This characteristic allows for fast and efficient system start-up, even after periods of shutdown, moreover it offers reduced mechanical strain on pumps and valves during cold starts.

• Globaltherm® GT06 operating range is -40 to °C to 290°C in bulk and up to 350°C in pressurised systems
• Globaltherm® GT06 delivers a high level of thermal stability which is critical for maintaining long-term system reliability and minimising downtime in mission-critical industrial processes
• The fluid is formulated for exceptional resistance to thermal degradation when managed correctly

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Parameter	Unit	Code (ASTM / ISO)	Result
Appearance	N/A	N/A	Pale yellow
Operating Range	°C (°F)	N/A	-40 to 350 (-40 to 662)
Density @ 20°C	kg/m³	ISO 12185	1008
Density at 100°C	kg/m³	ISO 12185	950
Kin. Viscosity -20°C	mm²/S	ISO3104	38.8
Kin. Viscosity +20°C	mm²/S	ISO 3104	5.90
Kin. Viscosity +60°C	mm²/S	ISO 3104	2.28
Flash Point PMC	°C	ISO 2592	140
Autoignition Point	°C		490
Pour Point	°C	ISO 3016	< -57
Acidity	mgKOH/g	ASTM D664	<0.02
Maximum Bulk Temperature	°C	NTR	350
Maximum Film Temperature	°C	NTR	370
Boiling point	NTR	NTR	290
Water	PPM	ASTM D6304	≤100

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Contact us for more information on synthetic heat transfer fluids.

Global Heat Transfer provides advice on how to extend fluid lifespan and provide business partners with continued technical support.

Call us on +44 (0)1785 760555 for more information.

Chemical composition is an important factor to consider when selecting a heat transfer fluid. Chemical composition will have an impact on the fluid’s properties, such as thermal stability and heat transfer efficiency. Matching the fluid to the system and the operating temperature can help to preserve fluid life.

 

While mineral heat transfer oils offer a good trade off between cost and performance, synthetic heat transfer fluids are the more popular choice in pharmaceutical applications. These have a lower susceptibility to form carbon than mineral based oils, offer better heat transfer efficiency and thermal stability, as well as a higher resistance to fouling.

Global Heat Transfer has over 30 years of experience in supplying and maintaining thermal fluid for the pharmaceutical industry.

A range of Globaltherm^® heat transfer fluids can be used for pharmaceutical batch processing because of their broad operating temperature range.

Proactive analysis and maintenance of heat transfer fluid is essential for pharmaceutical manufacturers. Thermal fluids degrade over time, particularly at high temperatures, reducing the efficiency of the system.

Regular thermal fluid analysis helps plant managers monitor oil condition. By taking a sample when the heat transfer system is hot, closed and circulating, plant managers get an accurate representation of the condition of the fluid inside the system.

After taking an accurate sample, plant managers can send the sample to thermal fluid experts, such as Global Heat Transfer, for analysis.  Regular sampling can also act as an early warning system, allowing plant managers to intervene and solve issues before they impact production.

At Global Heat Transfer we provide an extensive preventative maintenance programme, Thermocare.

Our expert engineers will work with you to improve accuracy when monitoring fluid, provide technical interventions when necessary, organise maintenance schedules and train staff. Our team also offers 24 hour engineering support to help you quickly diagnose and fix faults that can impact production.